BDBM25150 (2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide::Belinosta::Belinostat::PXD-101::PXD101

SMILES ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)Nc1ccccc1

InChI Key InChIKey=NCNRHFGMJRPRSK-MDZDMXLPSA-N

Data  21 KI  67 IC50  9 EC50  1 Other

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25150   

TargetHistone deacetylase 4 [653-1084,H976Y](Homo sapiens (Human))
Irbm/Merck Research Laboratories

LigandBDBM25150((2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2...)Copy SMILESCopy InChI

Affinity DataIC50:  24nMpH: 7.5 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPurchaseChEBI
MCE
PC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI